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Drug interactions : Anti-epileptic drugs (e.g., carbamazepine), anti-TB medication, and certain HIV treatments can reduce its effectiveness

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According to ClinVar, two pathogenic PRKN variants (p.R275W and p.Q34fs) were found in three PD patients, one PSP patient and three controls (all heterozygous, representing 0.46% of the total cohort, Table 3)

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